v.i. appl. 2 be very bitter. Amazima gatera okukaayirira abamu. The truth is usually very bitter for some people. Emmere abantu yabakaayirira. The people felt very bitter/the situation was very bad for them, lit. the food became bitter to the people, okukaayirirwa kaamu- lali omuntu gw'aba talidde, to have a bitter taste from peppers one has not eaten, i.e., become worried or involved in matters which do not concern one.